| Date | Fixture | Result | Score | Competition |
|---|---|---|---|---|
| 29 Jan 1927 | Liverpool v Southport | W | 3-1 | FA Cup |
| 15 Feb 1941 | Liverpool v Southport | L | 2-3 | League War Cup |
| 22 Feb 1941 | Southport v Liverpool | D | 2-2 | League War Cup |
| 14 Apr 1941 | Southport v Liverpool | L | 2-0 | North Region War League |
| 21 Nov 1942 | Southport v Liverpool | L | 3-2 | North Region War League |
| 28 Nov 1942 | Liverpool v Southport | W | 6-2 | North Region War League |
| 23 Jan 1943 | Liverpool v Southport | W | 3-1 | North Region War League (Second Championship) |
| 30 Jan 1943 | Southport v Liverpool | D | 2-2 | North Region War League (Second Championship) |
| 17 Apr 1943 | Liverpool v Southport | W | 3-0 | North Region War League (Second Championship) |
| 20 Nov 1943 | Liverpool v Southport | W | 9-0 | North Region War League |
| 27 Nov 1943 | Southport v Liverpool | W | 1-3 | North Region War League |
| 01 Apr 1944 | Liverpool v Southport | W | 6-2 | North Region War League (Second Championship) |
| 08 Apr 1944 | Southport v Liverpool | W | 4-7 | North Region War League (Second Championship) |
| 25 Dec 1944 | Southport v Liverpool | W | 1-4 | North Region War League (Second Championship) |
| 30 Dec 1944 | Liverpool v Southport | W | 12-1 | North Region War League (Second Championship) |
| 03 Mar 1945 | Southport v Liverpool | W | 0-5 | North Region War League (Second Championship) |