Trent Alexander-Arnold returns to the line-up from last Wednesday's fixture, as Nathaniel Clyne drops to the bench after making his first Liverpool appearance of the season against Everton this weekend.
Jordan Henderson's booking in the first leg means he faces a suspension tonight, with Gini Wijnaldum taking on the skipper's role in midfield. Alex Oxlade-Chamberlain and James Milner will partner the Dutch international, with the duo having both put in superb performances in the first leg.
Mohamed Salah, who came off during the second half in last week's first leg, has put aside a suspected groin pull to start, which will be a big boost for Jurgen Klopp's side.
Liverpool XI: Karius, Alexander-Arnold, Lovren, Van Dijk, Robertson, Milner, Wijnaldum, Oxlade-Chamberlain, Mane, Firmino, Salah.