The Liverpool goalkeeper started between the sticks ahead of Manchester City’s Ederson, keeping another clean-sheet in a comprehensive win for the Selecao.
Firmino was named on the substitutes bench and came on for Gabriel Jesus in the second-half, netting Brazil’s sixth goal of the night.
A lucky deflection saw the Reds forward through on goal as he made no mistake with a wonderful chipped finish past goalkeeper Luis Lopez.
Honduras, who were down to ten men in the first-half following a red card for winger Romell Quioto, failed to keep Tite’s rampant side at bay in the second-half, shipping a further four goals.
Jesus scored his second just two minutes after the break, with David Neres, Firmino and Everton’s Richarlison capping off a successful evening for Brazil, who were without talisman Neymar.
Brazil host this summer’s Copa America tournament, with their first fixture coming against Bolivia in five days time.
Alisson and Firmino are likely to play a major role in the competition. Fellow Liverpool midfielder Fabinho was a shock exclusion from manager Tite’s squad, despite a spectacular debut season at Anfield.
The final of the tournament, which Brazil are hugely favoured to reach, is scheduled for July 7 - three days after Liverpool return to pre-season training.
The duo will be given three weeks off to recover from this season’s antics, with a run to the final meaning they won’t return until Liverpool’s summer camp in France on July 28.
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