It was a crushing blow to Liverpool's top-four hopes, with the Reds seemingly unable to put together back-to-back Premier League wins or build up any momentum, allowing their rivals to steal a march on them in the race for Champions League qualification.
With teams breathing down their neck and four points separating Liverpool from a top-four place as it stands, Klopp's side desperately need to end their barren Anfield run and earn a much-needed three points against Fulham.
The visitors have shown a decent account of themselves in recent weeks despite a slim 1-0 defeat against Tottenham in their last outing and they should be in a confident mood to replicate what several sides have accomplished at Anfield this calendar year.
But Liverpool are beginning to run out of games to turn their season around and the hope is they can finish the season on a high starting with a valuable victory against the Cottagers.
Diogo Jota and Naby Keita will both be vying for a starting role after returning to full fitness and could offer the Reds a new dynamic in their attacking endeavours. The likes of Virgil van Dijk, Joe Gomez, Joel Matip and Jordan Henderson remain long-term absentees.
Updated: 13:00 (GMT)
Liverpool: . Substitutes: .
Fulham: . Substitutes: .
UK and USA TV Streaming
Liverpool vs Fulham is available to stream in the United Kingdom on Sky Sports, which is available on Sky channel 401 and Virgin Media channel 501.
Supporters in the United States can watch live on NBCSN at 09:00 (ET).
Worldwide TV Streaming
For viewers across the world, please refer to the list below for channels showing the game worldwide.
TSN GO, #Vamos, ESPN Play Sur, Idman TV, DIGI GO, ESPN2 Andina, Viaplay Denmark,Eurosport Player Denmark, Spiler1, Bongda TV, Sky Sport Uno, QQ Sports Live, Sky Sports Premier League Ireland, RDS GO, GO TV Anywhere, Kwese Live, SPOTV ON, Viasat Ultra HD, Now Player, 101 Soccer Streams, beIN Sports 1 Indonesia, beIN Sports 1 Thailand, SKY Go Italia, S Sport, Setanta Sports Kazakhstan, SuperSport 3 Africa, TV2 Sport Premium, Flow Sports 1, Flow Sports App, Now E, SCTV 17, Play Sports 1, Canal+ Sport 2 Afrique, TVPlay Sports, ESPN Brasil, Guangdong Sports Channel, Sky Sport Football, Match TV Football 1, Skynet Sports 6, Futbol 2, SportsNavi Live, Givemereddit Streams, RMC Sport en direct, Star Sports Select HD1, SL2G, BesTV,beIN SPORTS CONNECT, Sportklub 1 Croatia, Digiturk Play, Cytavision Sports 3, Optus Sport, Astro Supersport, FootyBite, TV3+ HD, TV2 Sumo, Viaplay Sweden, Cytavision Sports HD, SportKlub 1 Slovenia, Trees Network, NTV+ Sport Online, SBS, Ziggo Sport Select, RMC Sport 1, beIN Sports Connect New Zealand, Eurosport Romania, Hotstar, DAZN, Digi Sport 4, 102 (HD) mio Stadium, Diema Sport 2, Astro Go, SuperSport 3 Nigeria, ESPN2 Sur, Ziggo Sport 14, Viaplay Finland, SuperSport Maximo, 621 Now Premier League 1, Sky Pacific, Viasat Sports Premium, RDS 2, beIN Sports HD 11, Liveonscore, beIN Sports Connect Indonesia, SBS Live, TSN2 Malta, SportKlub 1 Serbia, Sky HD, PPTV Sport China, Kwese Free Sports, Star Sports Hindi 1, Ssports Live, Stod 2 Sport, TSN4, Watch ESPN Brasil, Viasat Football HD, Blue To Go Video Everywhere, Sport TV2, OLL.tv, S Sport+, 620 Now Premier League TV.