The Reds face Bayern Munich at the Allianz Arena, having been held to a stalemate in the first meeting at Anfield three weeks ago.
Liverpool boss Jurgen Klopp has named his 21-man squad to fly out to Munich, with the surprise exclusion of Naby Keita.
Keita is believed to have picked up a minor injury, although it is unclear exactly what the Guinean is suffering with.
Dejan Lovren is also included, although Klopp admitted that 90 minutes could be "too much" for the Croatian. Youngster Nat Phillips is on hand to provide cover.
Bayern vs Liverpool kicks off at 8pm on Wednesday night and you can keep up with all the drama via LFC Globe's live match-day coverage.
Liverpool's 21-Man Squad
Goalkeepers: Alisson, Mignolet, Kelleher
Defenders: Van Dijk, Matip, Lovren, Alexander-Arnold, Robertson, Moreno, Phillips
Midfielders: Fabinho, Wijnaldum, Henderson, Milner, Lallana
Forwards: Salah, Mane, Firmino, Shaqiri, Sturridge, Origi