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Liverpool need to win 1-0 or by a clear two-goal margin should they wish to progress to the knockout stages of the Champions League, or in the unlikely scenario of a PSG loss away to Red Star Belgrade, any win will do for Klopp's side.
The manager has made 3 changes to the side that he fielded on the south coast against Eddie Howe's side.
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson, Henderson, Milner, Wijnaldum, Salah, Firmino, Mane.
Substitutes: Mignolet, Fabinho, Lovren, Keita, Sturridge, Shaqiri, Origi.
Napoli: Ospina, Allan, Albiol, Koulibaly, Rui, Callejon, Ruiz, Mertens, Hamsik, Maksimovic, Insigne.
Substitutes: Karnezis, Ounas, Zielinski, Hysaj, Ghoulam, Diawara, Milik.