With another two games to go in December, Klopp will be hoping his side can retain their four-point over Manchester City ahead of their game in the New Year.
The boss may have had those fixtures against Arsenal and City in his mind as he makes three changes to the starting eleven that strutted out against Wolves.
Liverpool: Alisson, Alexander-Arnold, Lovren, Van Dijk, Robertson, Henderson, Wijnaldum, Shaqiri, Mane, Salah, Firmino.
Substitutes: Mignolet, Clyne, Fabinho, Keita, Sturridge, Lallana, Origi.
Newcastle: Dubravka, Lascelles, Fernandez, Dummett, Yedlin, Kenedy, Diame, Hayden, Ritchie, Joselu, Muto.
Substitutes: Schar, Manquillo, Woodman, Rondon, Murphy, Longstaff, Perez.