Liverpool supporters on social media reacted to Mane receiving treatment on his right knee after being substituted against the Dutch giants.
While there were no suggestions of an injury for the trio, Mane quietly made his way to the substitutes' bench before receiving treatment from the Reds backroom staff.
The forward was seen looking glum while icing his knee, which stirred worry among Liverpool supporters, who have already seen Virgil van Dijk ruled out for the season alongside injuries to Thiago and Joel Matip this week.
Speaking after the game, Klopp insisted there's no lasting damage for Mane, who has been struggling with a dead leg over the last two weeks.
“Sadio has still for a few days had a dead leg,” Klopp said. “He deals with it in that area, that’s the only thing.
“It is still painful but it’s not a problem. When he doesn’t play, he puts ice on it. That’s it.”
Here's how Liverpool supporters reacted prior to Klopp's comments...
Mane has ice wrapped around his right leg. #LFC could do without another injury.
— Ian Doyle (@IanDoyleSport) October 21, 2020
Mane getting iced up. pic.twitter.com/ritUjWPfkq
— Drebin (@CalvLyfeson) October 21, 2020
If you think I’m about to let a bit of ice on Mane’s leg worry me for the rest of the night .. you’re absolutely correct
— Kaye8a. (@KayethenLFC) October 21, 2020
Hoping Mane is ok. Ice pack on his knee 🤦♂️
— Spion Kop (@TheKopHQ) October 21, 2020
UHM MANÉ BETTER NOT BE INJURED, I SAW THAT ICE ON THE KNEE PLS DONT
— Lonita 🇽🇰🇦🇱 (@Lonita__) October 21, 2020
Mane with ice straight on his leg pic.twitter.com/zxd1pnoJ8y
— Stephen May (@StephenMay8) October 21, 2020
mané with ice on his knee i cba please be okay
— ayat (@Ifcayat) October 21, 2020
Mané having ice put on his leg God help us 🙃🙃🙃🙃
— LFCAdam 🇱🇧⚽❤ (@SalahFanV1) October 21, 2020
Seriously can't be fucked with Mane getting an injury aswell.
— Tim Bolton * (@timbolton1) October 21, 2020
Ugh should we be concerned they’re taping ice to Mane’s leg? Spare us injury gods.
— Mrinal Narang (@narangmrinal) October 21, 2020
If mane is ruled out with injury I’m done with football
— Zak (@ZakLFC7) October 21, 2020
Mane injury? pic.twitter.com/DxlyOc4ftM
— Bhokisi (@_Bhokisi) October 21, 2020