£104.1M
| Player | Club | Fee | Date |
|---|---|---|---|
| Marko Grujic | Red Star Belgrade | £5.1m | January 2016 |
| Steven Caulker | Queens Park Rangers | Loan | January 2016 |
| Kamil Grabara | Ruch Chorzow | £250,000 | January 2016 |
| Sadio Mané | Southampton | £30m | June 2016 |
| Loris Karius | Mainz 05 | £4.7m | July 2016 |
| Joël Matip | Schalke | Free | July 2016 |
| Ragnar Klavan | Augsburg | £4.2m | July 2016 |
| Alex Manninger | Free Agent | Free | July 2016 |
| Gini Wijnaldum | Newcastle United | £25m | July 2016 |
| Mohamed Salah | Roma | £43.9m | June 2017 |
| Dominic Solanke | Chelsea | £4m | July 2017 |
| Andy Robertson | Hull City | £10m | July 2017 |
| Alex Oxlade-Chamberlain | Arsenal | £35m | August 2017 |
| Virgil Van Dijk | Southampton | £75m | January 2018 |
| Naby Keita | Red Bull Leipzig | £52.75m | July 2018 |
| Fabinho Tavarez | AS Monaco | £43.7m | July 2018 |
| Xherdan Shaqiri | Stoke City | £13.75m | July 2018 |
| Alisson Becker | Roma | £65m | July 2018 |
| Sepp van den Berg | PEC Zwolle | £4.4m | June 2019 |
| Harvey Elliott | Fulham | Compensation | July 2019 |
| Adrián San Miguel | Free Agent | Free | August 2019 |
| Andy Lonergan | Free Agent | Free | August 2019 |
| Takumi Minamino | Red Bull Salzburg | £7.25m | January 2020 |
| Kostas Tsimikas | Olympiacos | £11.75m | August 2020 |
| Thiago Alcantara | Bayern Munich | £27.4m | September 2020 |
| Diogo Jota | Wolves | £45m | September 2020 |
Gross spend on transfers: £508.1m
| Player | Club | Fee | Date |
|---|---|---|---|
| Jose Enrique | Released | Free | July 2016 |
| Kolo Touré | Released | Free | July 2016 |
| Jordan Rossiter | Released | Free | July 2016 |
| João Carlos Teixeira | Released | Free | July 2016 |
| Jerome Sinclair | Released | Free | July 2016 |
| Samed Yesil | Released | Free | July 2016 |
| Sergi Canos | Norwich City | £4.5m | July 2016 |
| Martin Skrtel | Fenerbahce | £5.5m | July 2016 |
| Jordon Ibe | Bournemouth | £15m | July 2016 |
| Joe Allen | Stoke City | £13m | July 2016 |
| Brad Smith | Bournemouth | £6m | July 2016 |
| Christian Benteke | Crystal Palace | £32m | August 2016 |
| Luis Alberto | Lazio | £6m | August 2016 |
| Mario Balotelli | OGC Nice | Free | August 2016 |
| Tiago Ilori | Reading | £3.75m | January 2017 |
| Jack Dunn | Released | Free | July 2017 |
| Alex Manninger | Released | Free | July 2017 |
| Andre Wisdom | Derby County | £4.5m | July 2017 |
| Lucas Leiva | Lazio | £5m | July 2017 |
| Ryan Fulton | Hamilton Academical | Free | July 2017 |
| Kevin Stewart | Hull City | £8m | July 2017 |
| Mamadou Sakho | Crystal Palace | £26m | August 2017 |
| Philippe Coutinho | Barcelona | £142m | January 2018 |
| Cameron Brannagan | Oxford United | £200,000 | January 2018 |
| Emre Can | Released | Free | July 2018 |
| Danny Ward | Leicester City | £12.5m | July 2018 |
| Ragnar Klavan | Cagliari | £2m | August 2018 |
| Dominic Solanke | Bournemouth | £19m | January 2019 |
| Lazar Markovic | Fulham | Free | January 2019 |
| Rafael Camacho | Sporting Lisbon | £7m | June 2019 |
| Daniel Sturridge | Released | Free | July 2019 |
| Alberto Moreno | Released | Free | July 2019 |
| Adam Bogdan | Released | Free | July 2019 |
| Connor Randall | Released | Free | July 2019 |
| Danny Ings | Southampton | £20m | July 2019 |
| Simon Mignolet | Club Brugge | £8.2m | August 2019 |
| Ryan Kent | Rangers | £7.5m | September 2019 |
| Bobby Duncan | Fiorentina | £1.8m | September 2019 |
| Allan Rodrigues de Souza | Atletico Mineiro | £3.2m | January 2020 |
| Pedro Chirivella | Released | Free | July 2020 |
| Nathaniel Clyne | Released | Free | July 2020 |
| Andy Lonergan | Released | Free | July 2020 |
| Dejan Lovren | Zenit Saint Petersburg | £10.9m | July 2020 |
| Adam Lallana | Released | Free | July 2020 |
| Ovie Ejaria | Reading | £3.5m | August 2020 |
| Ki-Jana Hoever | Wolves | £13.5m | September 2020 |
| Rhian Brewster | Sheffield United | £23.5m | 2 October 2020 |
Gross received from transfers: £404m