But with one more game to go and more records still within their grasp, Jurgen Klopp's side will be keen to end their remarkable campaign on a high.
We'll have all the latest from Tyneside throughout the day, including confirmed team news, live commentary and post-match reaction.
Liverpool: Alisson, Williams, Gomez, Van Dijk, Robertson, Milner, Wijnaldum, Keita, Oxlade-Chamberlain, Minamino, Origi. Substitutes: Adrian, Fabinho, Firmino, Mane, Salah, Shaqiri, Jones, Alexander-Arnold, Elliott.
Newcastle: Dubravka, Manquillo, Fernandez, Rose, Ritchie, Bentaleb, Shelvey, Lazaro, Almiron, Saint-Maxim, Gayle. Substitutes: Darlow, Carroll, Joelinton, Muto, Hayden, Yedlin, Longstaff, Watts, Young.
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