The Reds had their crowning moment in midweek as they lifted the league title after 30 years following a 5-3 victory over Chelsea at Anfield.
But with one more game to go and more records still within their grasp, Jurgen Klopp's side will be keen to end their remarkable campaign on a high.
We'll have all the latest from Tyneside throughout the day, including confirmed team news, live commentary and post-match reaction.
Liverpool: Alisson, Williams, Gomez, Van Dijk, Robertson, Milner, Wijnaldum, Keita, Oxlade-Chamberlain, Minamino, Origi. Substitutes: Adrian, Fabinho, Firmino, Mane, Salah, Shaqiri, Jones, Alexander-Arnold, Elliott.
Newcastle: Dubravka, Manquillo, Fernandez, Rose, Ritchie, Bentaleb, Shelvey, Lazaro, Almiron, Saint-Maxim, Gayle. Substitutes: Darlow, Carroll, Joelinton, Muto, Hayden, Yedlin, Longstaff, Watts, Young.
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