They now resume their European campaign as they host Porto in their penultimate Group B fixture, having already clinched qualification to the knockout stages as group winners with a 2-0 win over Atletico Madrid in their last outing.
Whilst there is little riding on the game for the Reds, the visitors will undoubtedly be looking for every advantage they can get given they sit just one point ahead of third-placed Atletico in the table, who could go above them with a win tonight before the two sides meet on the final matchday.
The Reds will therefore need to avoid any hints of complacency if they wish to extend their lead at the top of the group, with the hope they can put in one of their routine displays under the lights at Anfield.
A repeat display from the 5-1 win over the visitors in the reverse fixture would be a welcome sight, although the priority for Klopp and co will undoubtedly be to avoid any injuries during what is the busiest time of the season.
Liverpool will once again make a late call on the involvement of captain Jordan Henderson and left-back Andy Robertson. The Reds skipper came on from the bench at the weekend having picked up a knock on international duty last week, whilst Robertson was absent altogether.
Meanwhile, James Milner and Divock Origi could be involved in the matchday squad after returning to full team training on Tuesday. However, the Reds are still without the services of Joe Gomez, Naby Keita, Curtis Jones, Harvey Elliott and Roberto Firmino.
Updated: 18:45 (BST)
Liverpool: Alisson, N. Williams, Matip, Konate, Tsimikas, Morton, Thiago, Oxlade-Chamberlain, Salah, Minamino, Mane. Substitutes: Adrian, Kelleher, Fabinho, Van Dijk, Milner, Henderson, Robertson, Origi, Phillips, Alexander-Arnold.
Porto: Costa, Mario, Pepe, Mbemba, Zaidu, Otavio, Uribe, Oliveira, Diaz, Taremi, Evanilson. Substitutes: Marchesin, Cardoso, Conceicao, Pepe, Grujic, Corona, Manafa, Vitinha, Wendell, Bruno Costa, Martinez, Vieira.
UK and USA TV Streaming
Liverpool vs Porto is available to stream in the United Kingdom on BT Sport 3, which is available on Sky channel 417 and Virgin Media channel 529.
Supporters in the United States can watch live on Paramount+ at 15:00 (ET).
Worldwide TV Streams
For viewers across the world, please refer to the list below for channels showing the game worldwide.
Futbol 2, beIN Sports 1 Indonesia, PPTV Sport China, Canal+ Sport Online, C More Suomi, SBS ESPN Korea, RMC Sport 1, J Sports 2, MaxTV Go, SONY TEN 2, KAZsport, Viasat Ultra HD, beIN SPORTS CONNECT, Viaplay Finland, Astro Go, Sky Sport 3 HD Italia, Arena Sport 3 Serbia, TSN GO, O2 TV, TV2 Sport , Viaplay Sweden, Cytavision Sports HD, TSN4, TDM Desporto, SONY TEN 2 HD, TNT Brazil, NTV+ Sport Online, ESPN2 Andina, TSN5, TSN3,beIN Sports Connect Hong Kong, beIN Sports Arabia 2 HD,Tring Sport 1, Astro SuperSport 3, Look Plus, Setanta Sports Kazakhstan, Viasat Football HD, Viaplay Denmark, Sport TV3, TV2 Sumo, Orange Sport 1,beIN Sports HD 11, SuperSport 3, beIN Sports Connect Thailand, Optus Sport, Eurosport Player Denmark, SPS HD,02 (HD) mio Stadium, NTV+ Sport Online, SKY Planeta Futbol, Reddit Soccer Streams, TNT Go, DAZN, Optus Sport, RTE 2, Futbol 2, M4 Sports, ESPN Brasil, Ziggo Sport Select, Idman TV, RCTI, FBC Sports, Viaplay Denmark, SuperSport 3 Africa,Cytavision Live, Viasat Ultra HD, Flow Sports App, Footybite, Sky Sport Football, DAZN Europe, Viasat Sports Premium, Sky Sport Austria, Telekom Sport 1 Romania, Ssports Live, Idman TV, Astro Go, SuperSport Maximo, QQ Sports Live, SBS Live, SuperSport 3 Nigeria, Kanal A, Movistar+, TV2 Sumo, SuperSport 5 Africa, Digiturk Play, 620 PLTV