The Reds boss makes four changes to the side that beat Leicester ahead of the international break as goalkeeper Alisson, Joel Matip and Jordan Henderson return. Divock Origi replaces Mohamed Salah, who is not in the match-day squad due to an ankle knock.
Liverpool: Alisson, Alexander-Arnold, Matip, Van Dijk, Robertson, Fabinho, Henderson, Wijnaldum, Mane, Origi, Firmino.
Substitutes: Adrian, Lovren, Milner, Keita, Gomez, Oxlade-Chamberlain, Lallana.
Manchester United: De Gea, Wan Bissaka, Lindelof, Maguire, Rojo, McTominay, Fred, James, Andreas, Young, Rashford.
Substitutes: Romero, Jones, Williams, Garner, Mata, Greenwood, Martial.