Should either side win on Wednesday night, victory would see them guarantee qualification to the next stage of the Champions League.
It appears that Tuchel is ready to roll the dice with a bold team selection, according to French outlet RMC Sport.
According to the report, Neymar and Kylian Mbappe will both recover in time for the clash, despite missing this weekend's 1-0 win over Toulouse. The duo will start alongside Edinson Cavani in attack, but it's the team behind them that will be 'surprising'.
Thilo Kehrer is set to play at right back against Sadio Mane, whilst Brazilian defender Marquinhos will make a move into midfield.
Both defenders usually play in the centre of defence, but Tuchel will move them around, possibly in response to the Reds' 3-2 win over them at Anfield earlier in the campaign.
Kehrer will start in a back-line of Thiago Silva, Presnel Kimpembe and Juan Bernat. Whilst Marquinhos is expected to be in a midfield three of Angel di Maria and Marco Verratti.
Whilst the selection is predominantly a 4-3-3, RMC claim that it could turn to a 3-4-3 depending on Liverpool's shape and tactics.
Adrien Rabiot and Thomas Meunier, both who started at Anfield, are expected to be named on the bench, along with Julian Draxler.
RMC's possible PSG lineup: Buffon; Kehrer, Thiago Silva, Kimpembe, Bernat; Di Maria, Marquinhos, Verratti; Mbappé, Cavani, Neymar.