It's the biggest game of the Premier League season so far for the Reds as they look to return to winning ways with a much-needed three points against Pep Guardiola's side on Sunday afternoon.
The champions appeared to have turned things around following an extended slump in their campaign with away wins over Tottenham and West Ham, but a shock defeat against Brighton at Anfield in midweek puts the pressure back on Liverpool should they wish to keep pace with their title rivals.
It's no surprise Jurgen Klopp looked to ease expectations in the build-up to the crunch clash, with the Reds boss insisting his side aren't in the title race at present given their inconsistent form of late.
Meanwhile, the visitors should be in confident mood to pick up their first win at Anfield since 2003, with last year's runners up putting together a run of 13 consecutive wins, including clean sheets in each of their last seven games.
But if Liverpool harbour any hopes of retaining their Premier League crown, this is undeniably a game they have to win in order to catch up with City and narrow the seven-point gap between the two sides. It's set to be an intriguing 90 minutes on a chillingly cold day at Anfield...
Liverpool's injury woes were partially eased this week as Alisson, Fabinho and Sadio Mane all returned to training at Kirkby and the trio look set to come straight back into the side.
While Klopp opted to stick with a defensive pairing of Nathaniel Phillips and Jordan Henderson in midweek, new boys Ben Davies and Ozan Kabak will be hoping for their first Reds start after signing on deadline day. But it remains to be seen whether Klopp chooses to throw either of them in at the deep end.
Updated: 15:30 (GMT)
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Man City: . Substitutes: .
UK and USA TV Streaming
Liverpool vs Man City is available to stream in the United Kingdom on Sky Sports Main Event, which is available on Sky channel 401 and Virgin Media channel 501.
Supporters in the United States can watch live on NBCSN at 11:30 (ET).
Worldwide TV Streaming
For viewers across the world, please refer to the list below for channels showing the game worldwide.
Cytavision Live, TV2 Sumo, beIN Sports HD 11,Futbol 2, SONY TEN 2, FBC Sports, SuperSport 5 Africa,Tring Sport 1, TNT Go, Movistar+, NTV+ Sport Online, TDM Desporto, DAZN, C More Suomi, beIN SPORTS CONNECT, TV2 Sport , M4 Sports, Cytavision Sports HD, SONY TEN 2 HD, KAZsport, Viasat Ultra HD, RMC Sport 1, TNT Brazil, O2 TV, Optus Sport, Astro Go, Orange Sport 1, MaxTV Go, Sky Sport Austria, RCTI, Viaplay Denmark, Sky Sport Football, Arena Sport 3 Serbia, RTE 2, Look Plus, Telekom Sport 1 Romania,beIN Sports Connect Hong Kong, Kanal A, Astro SuperSport 3, Footybite, RMC Sport en direct, Viaplay Sweden, TVPlay Sports, Eleven Sports 2 Portugal, Klik SPORT, SuperSport 5 Nigeria, SKY Go Italia, Virgin TV Go, 602 HD Sports 2, Match TV Football 1, GO TV Anywhere, Cytavision Sports 1, Proximus 11+, Soccer Streams, Digi Sport 1 Romania, MAX Sport 2, 662 Sports 2, Cosmote Sport 3 HD, Ziggo Sport Voetbal, Telekom TV Live, Fox Sports Cono Sur, Fox Sports Cono Norte, Esporte Interativo Plus, Sony LIV, Planet Sport 1, beIN Sports HD 1, TV3+ HD, Teleclub Sport 2 / Sky Sport 2, Idman TV, Skynet Myanmar, Stod 2 Sport, IPLA, Polsat Sport Premium 3, C More Sport 1, TSN1 Malta, Viasat Sports Premium, Sky Calcio 3,K-Vision, Sky Sport 3 NZ./em>