The Reds return to league action as they look for three points against Ralph Hasenhuttl's side, against whom they hold an exceptional record at Anfield, with Liverpool unbeaten since 2013.
We'll have all the latest throughout the day, including confirmed team news, live social media updates, and post-match reaction.
Liverpool: Alisson, Alexander-Arnold, Konate, Van Dijk, Robertson, Fabinho, Henderson, Thiago, Salah, Jota, Mane. Substitutes: Kelleher, Milner, Oxlade-Chamberlain, Minamino, Tsimikas, Origi, Matip, Williams, Morton.
Southampton: McCarthy, Lyanco, Romeu, Ward-Prowse, Armstrong, Adams, Perraud, Broja, Livramento, Salisu, Bednarek. Substitutes: Forster, Walker-Peters, Long, Redmond, Smallbone, Tella, Diallo, Walcott, Valery..
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