The Reds are looking to get back to winning ways after their defeat in midweek, however Rafa Benitez's side at home could prove to be a dangerous opposition.
The manager makes four changes to the side that started at Camp Nou as Daniel Sturridge leads the line.
Liverpool: Alisson, Alexander-Arnold, Lovren, Van Dijk, Robertson, Fabinho, Wijnaldum, Henderson, Mane, Salah, Sturridge.
Substitutes: Mignolet, Milner, Gomez, Oxlade-Chamberlain, Shaqiri, Origi, Matip.
Newcastle: Dubravka, Manquillo, Schar, Lascelles, Dummett, Ritchie, Hayden, Ki, Atsu, Perez, Rondon.
Substitutes: Darlow, Barreca, Fernandez, Kenedy, Shelvey, Diame, Muto.