The Reds travel to Stamford Bridge for their first away game of the season as they look for their fifth win in six previous games against the Blues.
Frank Lampard’s side started the season with a 3-1 win over Brighton last weekend, with new signings Timo Werner and Kai Havertz making their debuts.
Chelsea’s other summer additions – Ben Chilwell, Thiago Silva and Hakim Ziyech – didn’t feature at the Amex and Lampard ruled them out for Sunday’s clash.
Despite three of the Blues’ new signings unable to take to the field, Klopp is adamant Liverpool will need to be at their sharpest against a “tricky” side.
He told his pre-match press conference on Friday: “Last year we played Chelsea pretty often and pretty early in the season. All the games were really difficult, so that’s what I expect, first and foremost.
“The first game against Brighton was how it looks when you play Brighton. I’m not sure but when you play Brighton we all suffer because they just play good football and you have to be decisive in the key moments and that was the story of the game pretty much.
“Pretty early it’s clear we actually have absolutely no idea who Frank will line up – so many different options.
“Because we don’t know a lot about Chelsea in the moment – during the season that will probably change – we just have to focus on ourselves. There’s enough work to do with that for different reasons.
“We are very early in the season, so we had an intense week of work. [We] worked – how we see it – on decisive stuff.
“A lot of things were good in the first game, some things were not that good. I know that but it’s the first game, so we don’t make it less important or more important than necessary, just work with it and use it as one information.
“All the rest of the week was absolutely good so far. So now we have to make sure that we can transform that on the pitch because we better be at our best otherwise it could be really, really tricky.”
The boss had nothing to add regarding fitness concerns ahead of the trip, with only Alex Oxlade-Chamberlain sidelined.
“Intense week. A few little things here and there but in the moment should be OK,” Klopp said.
“Nobody is coming back or whatever, and the rest we have to see. So, still two days to go – two training sessions – but for the moment, we seem OK.”
Watch Klopp’s press conference in full above.